Maxim Artyomov, PhD

Maxim Artyomov, PhD

Primary Academic Title

Associate Professor of Pathology and Immunology, Division of Immunobiology, Washington University School of Medicine

Research Interest

Systems immunology using cross-disciplinary approaches to data generation and analysis; novel fundamental biology in immunometabolism, cancer immunology and aging; single-cell RNA-sequencing, transcriptional data analysis, chip-sequencing, metabolomics, data integration, peptide-MHC binding

Education

  • 2009: PhD, Massachusetts Institute of Technology

Training

  • 2009 - 2012: Postdoctoral fellow, Broad Institute of MIT & Harvard, Cambridge, Mass.

Selected Research Publications

T cell control of inflammaging.
  • Shchukina I, Bohacova P, Artyomov MN
  • Semin Immunol 2023
Reduction of SPARC protects mice against NLRP3 inflammasome activation and obesity.
  • Ryu S, Spadaro O, Sidorov S, [...] Artyomov MN, [...] Dixit VD
  • J Clin Invest 2023
Costimulatory domains direct distinct fates of CAR-driven T-cell dysfunction.
  • Selli ME, Landmann JH, Terekhova M, [...] Artyomov M, Singh N
  • Blood 2023
Systems Immunology Approaches to Metabolism.
  • Mogilenko DA, Sergushichev A, Artyomov MN
  • Annu Rev Immunol 2023
The matricellular protein SPARC induces inflammatory interferon-response in macrophages during aging.
  • Ryu S, Sidorov S, Ravussin E, Artyomov M, [...] Dixit VD
  • Immunity 2022
Immune ageing at single-cell resolution.
  • Mogilenko DA, Shchukina I, Artyomov MN
  • Nat Rev Immunol 2022
Shiny GATOM: omics-based identification of regulated metabolic modules in atom transition networks.
  • Emelianova M, Gainullina A, Poperechnyi N, [...] Artyomov M, Sergushichev A
  • Nucleic Acids Res 2022
Caloric restriction in humans reveals immunometabolic regulators of health span.
  • Spadaro O, Youm Y, Shchukina I, [...] Artyomov MN, Dixit VD
  • Science 2022
Semi-supervised peak calling with SPAN and JBR genome browser.
  • Shpynov O, Dievskii A, Chernyatchik R, Tsurinov P, Artyomov MN
  • Bioinformatics 2021
Regulation of olfactomedin 4 by Porphyromonas gingivalis in a community context.
  • Fitzsimonds ZR, Liu C, Stocke KS, [...] Artyomov MN, [...] Lamont RJ
  • ISME J 2021
Radiation-induced neoantigens broaden the immunotherapeutic window of cancers with low mutational loads.
  • Lussier DM, Alspach E, Ward JP, [...] Artyomov MN, [...] Schreiber RD
  • Proc Natl Acad Sci USA 2021

View All Publications