Edwin Antony, PhD

Edwin Antony, PhD

Primary Academic Title

Associate Professor, Biochemistry and Molecular Biology, Saint Louis University

Research Interest

Molecular mechanisms of DNA repair, recombination and genomic instability


  • 2005: PhD, biochemistry and molecular biology, Wesleyan University, Middletown, Conn.


  • 2005 - 2006: Post-doctoral research fellow, biomedical engineering, Johns Hopkins University, Baltimore
  • 2006 - 2010: Post-doctoral research fellow, biochemistry and molecular biophysics, Washington University, St. Louis

Selected Research Publications

Fluorescent human RPA to track assembly dynamics on DNA.
  • Kaushik V, Chadda R, Kuppa S, [...] Antony E
  • Methods 2024
Yeast Rad52 is a homodecamer and possesses BRCA2-like bipartite Rad51 binding modes.
  • Deveryshetty J, Chadda R, Mattice JR, [...] Antony E
  • Nat Commun 2023
An Aurora B-RPA signaling axis secures chromosome segregation fidelity.
  • Roshan P, Kuppa S, Mattice JR, [...] Antony E, Origanti S
  • Nat Commun 2023
Dynamic states of eIF6 and SDS variants modulate interactions with uL14 of the 60S ribosomal subunit.
  • Elliff J, Biswas A, Roshan P, [...] Antony E, [...] Origanti S
  • Nucleic Acids Res 2023
Rtt105 regulates RPA function by configurationally stapling the flexible domains.
  • Kuppa S, Deveryshetty J, Chadda R, [...] Antony E
  • Nat Commun 2022
Human HELB is a processive motor protein that catalyzes RPA clearance from single-stranded DNA.
  • Hormeno S, Wilkinson OJ, Aicart-Ramos C, [...] Antony E, [...] Moreno-Herrero F
  • Proc Natl Acad Sci USA 2022