Steven Brody, MD

Steven Brody, MD

Primary Academic Title

Professor of Medicine, Division of Pulmonary and Critical Care Medicine, Washington University School of Medicine

Research Interest

Airway epithelial cell differentiation in development and alterations that may occur during inflammatory diseases and carcinogenesis. We have used mouse and primary epithelial cell models to determine molecular steps required for normal differentiation and particulary investigated proteins required for ciliogenesis. Key words: epithelial, lung, airway, polarity, cilia, differentiation, mucus, mouse, cytoskeleton. From ICTS Profile: Our research focus is abnormalities of the airway epithelial cell differentiation that characterize lung diseases such as bronchitis, bronchiectasis, respiratory virus and bacterial infection. We are particularly interested in mechanisms of ciliated cell differentiation and cilia biogenesis. These studies are linked to investigation of the genetic basis of lung disease in patient populations with known or suspected defects in cilia, co-called ciliopathies.

Education

  • 1980: MD, University of Michigan, Ann Arbor

Training

  • 1980 - 1983: Resident, internal medicine, University of Cincinnati
  • 1989 - 1993: Fellow, pulmonary medicine, Pulmonary Branch, National Heart, Lung and Blood Institute, Bethesda, Md.
  • 1994 - 1995: Postdoctoral fellow, developmental biology, Washington University, St. Louis

Selected Research Publications

Magnify is a universal molecular anchoring strategy for expansion microscopy.
  • Klimas A, Gallagher BR, Wijesekara P, [...] Brody SL, [...] Zhao Y
  • Nat Biotechnol 2023

View All Publications