Marina Cella, MD

Marina Cella, MD

Primary Academic Title

Professor of Pathology and Immunology, Washington University School of Medicine

Research Interest

My interest focuses on Type 3 Innate Lymphoid Cells (ILC3) present at mucosal sites. The cell type depends on the transcription factor Aryl Hydrocarbon Receptor (AHR) for development, maintenance and function. I'm interested in understanding whether AHR ligands (agonist/antagonist) modulate ILC3 during obesity and whether this affects colon cancer development.

Education

  • 1989: MD, University of Genova School of Medicine, Genova, Italy

Training

  • 1989 - 1993: Fellow, immunogentics, National Institute for Cancer Research, Genova, Italy

Selected Research Publications

The transcription factor Aiolos restrains the activation of intestinal intraepithelial lymphocytes.
  • Yomogida K, Trsan T, Sudan R, [...] Cella M, [...] Colonna M
  • Nat Immunol 2024
A distinct human cell type expressing MHCII and RORγt with dual characteristics of dendritic cells and type 3 innate lymphoid cells.
  • Ulezko Antonova A, Lonardi S, Monti M, [...] Cella M, [...] Colonna M
  • Proc Natl Acad Sci USA 2023
TREM2: A new player in the tumor microenvironment.
  • Molgora M, Liu YA, Colonna M, Cella M
  • Semin Immunol 2023
Hobit confers tissue-dependent programs to type 1 innate lymphoid cells.
  • Yomogida K, Bigley TM, Trsan T, [...] Cella M, [...] Colonna M
  • Proc Natl Acad Sci USA 2021
Immunodeficiency and bone marrow failure with mosaic and germline TLR8 gain of function.
  • Aluri J, Bach A, Kaviany S, [...] Cella M, [...] Cooper MA
  • Blood 2021