Aaron DiAntonio, MD, PhD

Aaron DiAntonio, MD, PhD

Primary Academic Title

Professor of Developmental Biology, Washington University School of Medicine

Research Interest

Synapses change as neuronal circuits develop and are modified by experience. We study the molecular mechanisms that underlie the maturation of synaptic structure and function during development. We use the Drosophila neuromuscular junction as a model system because of the ease with which genetic, molecular, anatomical and electrophysiological techniques can be combined.

Education

  • 1989: MPhil, biochemistry, Cambridge University, Cambridge, England
  • 1995: MD/PhD, physiology, Stanford University, Stanford, Calif.

Training

  • 1995 - 1999: Postdoctoral fellow, developmental biology, University of California, Berkeley

Selected Research Publications

Pmp2+ Schwann Cells Maintain the Survival of Large-Caliber Motor Axons.
  • Kozlowski MM, Strickland A, Benitez AM, [...] DiAntonio A
  • J Neurosci 2025
Macrophage depletion blocks congenital SARM1-dependent neuropathy.
  • Dingwall CB, Strickland A, Yum SW, [...] DiAntonio A, Milbrandt J
  • J Clin Invest 2022
Distinct developmental and degenerative functions of SARM1 require NAD+ hydrolase activity.
  • Brace EJ, Essuman K, Mao X, [...] DiAntonio A
  • PLoS Genet 2022

View All Publications