Susana Gonzalo, PhD

Susana Gonzalo, PhD

Primary Academic Title

Associate Professor, Department of Biochemistry and Molecular Biology, Doisy Research Center,Saint Louis University School of Medicine

Research Interest

Our research aims to understand molecular mechanisms that contribute to the genomic instability that drives aging and cancer. We place special emphasis on cancers with the poorest prognosis, such is the case of BRCA1 mutated and triple negative breast cancers, and premature aging disorders such as Hutchinson Gilford Progeria Syndrome. Interestingly, we have identified common pathways in both types of disease, and are testing possible therapeutic strategies to ameliorate genomic instability in both contexts.


  • 1999: PhD, molecular cell biology, Washington University, St. Louis


  • 1999 - 2992: Postdoctoral fellow, molecular oncology, Washington University, St. Louis
  • 2002 - 2006: Postdoctoral fellow, molecular oncology, Spanish National Cancer Research Center, Madrid

Selected Research Publications

Lamin A/C recruits ssDNA protective proteins RPA and RAD51 to stalled replication forks to maintain fork stability.
  • Graziano S, Coll-Bonfill N, Teodoro-Castro B, [...] Gonzalo S
  • J Biol Chem 2021