Allegra Petti, PhD

Allegra Petti, PhD

Primary Academic Title

Assistant Professor of Medicine, Division of Oncology, Washington University School of Medicine

Research Interest

Gene regulation at single-cell resolution during the development and evolution of cancer, the study of intratumoral expression heterogeneity in acute myeloid leukemia

Education

  • 2005: PhD, genetics, Harvard Medical School, Boston

Training

  • 2005 - 2006: Postdoctoral fellow, Harvard Medical School, Boston
  • 2006 - 2011: Postdoctoral fellow, Princeton University, Princeton, N.J.

Selected Research Publications

T-BET and EOMES sustain mature human NK cell identity and antitumor function.
  • Wong P, Foltz JA, Chang L, [...] Petti AA, [...] Fehniger TA
  • J Clin Invest 2023
TREM2 inhibition triggers antitumor cell activity of myeloid cells in glioblastoma.
  • Sun R, Han R, McCornack C, [...] Petti A, [...] Kim AH
  • Sci Adv 2023
Donor memory-like NK cells persist and induce remissions in pediatric patients with relapsed AML after transplant.
  • Bednarski JJ, Zimmerman C, Berrien-Elliott MM, [...] Petti AA, [...] Fehniger TA
  • Blood 2022
Hematopoietic cell transplantation donor-derived memory-like NK cells functionally persist after transfer into patients with leukemia.
  • Berrien-Elliott MM, Foltz JA, Russler-Germain DA, [...] Petti AA, [...] Fehniger TA
  • Sci Transl Med 2022
Competitive binding of E3 ligases TRIM26 and WWP2 controls SOX2 in glioblastoma.
  • Mahlokozera T, Patel B, Chen H, [...] Petti AA, [...] Kim AH
  • Nat Commun 2021
Phase I Trial of N-803, an IL15 Receptor Agonist, with Rituximab in Patients with Indolent Non-Hodgkin Lymphoma.
  • Foltz JA, Hess BT, Bachanova V, [...] Petti AA, [...] Fehniger TA
  • Clin Cancer Res 2021