Ryan Fields, MD

Ryan Fields, MD


Primary Academic Title

Chief, Section of Surgical Oncology; Professor of Surgery, Division of General Surgery, Washington University School of Medicine

Clinical Expertise

As chief of the Section of Surgical Oncology and as a member of our sarcoma, pancreatic, liver, bile duct, stomach and skin cancer specialist teams, Dr. Fields is committed to providing patients with exceptional care.

Research Interest

The identification and treatment of patients at high risk for recurrence of their cancer and the use of novel treatment modalities to improve survival.


  • 2003: MD, Duke University, Durham, N.C.


  • 2003 - 2005: Resident, general surgery, Washington University, St. Louis
  • 2005 - 2006: Research fellow, surgery and immunology, Washington University
  • 2006 - 2009: Resident and chief resident, general surgery, Washington University
  • 2009 - 2011: Fellow, surgical oncology, Memorial Sloan-Kettering Cancer Center, New York

Board Certification

  • 2009: American Board of Surgery, General Surgery

Selected Research Publications

Senescence Defines a Distinct Subset of Myofibroblasts That Orchestrates Immunosuppression in Pancreatic Cancer.
  • Belle JI, Sen D, Baer JM, [...] Fields RC, [...] DeNardo DG
  • Cancer Discov 2024
Senescence defines a distinct subset of myofibroblasts that orchestrates immunosuppression in pancreatic cancer.
  • Belle JI, Sen D, Baer JM, [...] Fields RC, [...] DeNardo DG
  • Cancer Discov 2024
Epigenetic regulation during cancer transitions across 11 tumour types.
  • Terekhanova NV, Karpova A, Liang WW, [...] Fields RC, [...] Ding L
  • Nature 2023
Fibrosis induced by resident macrophages has divergent roles in pancreas inflammatory injury and PDAC.
  • Baer JM, Zuo C, Kang LI, [...] Fields RC, [...] DeNardo DG
  • Nat Immunol 2023
Systemic Alterations in Type-2 Conventional Dendritic Cells Lead to Impaired Tumor Immunity in Pancreatic Cancer.
  • James CA, Baer JM, Zou C, [...] Fields RC, [...] DeNardo DG
  • Cancer Immunol Res 2023
Autologous humanized PDX modeling for immuno-oncology recapitulates features of the human tumor microenvironment.
  • Chiorazzi M, Martinek J, Krasnick B, [...] Fields RC, Flavell RA
  • J Immunother Cancer 2023
Context-dependent activation of STING-interferon signaling by CD11b agonists enhances anti-tumor immunity.
  • Liu X, Hogg GD, Zuo C, [...] Fields RC, [...] DeNardo DG
  • Cancer Cell 2023
CD5 expression by dendritic cells directs T cell immunity and sustains immunotherapy responses.
  • He M, Roussak K, Ma F, [...] Fields RC, [...] Klechevsky E
  • Science 2023

View All Publications

Contact Information

  • West St. Louis County

    Medical Office Building 2, 10 Barnes West Drive
    Creve Coeur, MO 63141

  • Washington University Medical Campus

    4921 Parkview Place
    Saint Louis, MO 63110

Phone Numbers

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