Linda Sandell, PhD

Linda Sandell, PhD

Primary Academic Title

Professor of Orthopaedic Surgery and of Cell Biology and Physiology, Washington University School of Medicine

Research Interest

MIA/CD-RAP is a small secrected protein found in melanoma, breast cancers and chondrosarcoma. It is believed to regulate interaction between cells and extracellular components. The normal distribution of MIA/CD-RAP is primarily in developing cartilage and has recently been found in pre-mammary gland. This gene is expressed during development, repressed and re-expressed after transformation and therefore is classified as onco-fetal gene. MIA/CD-RAP is currently being used to monitor for recurrent melanoma and could be a useful marker for breast cancer and chondrosarcoma. Key words: CD-RAP, chondrosarcoma, melanoma, breast cancer, gene expression, MRNA splicing.


  • 1971: MS, biological science, Denver University
  • 1980: PhD, biochemistry, Northwestern University, Chicago