Amanda Smith, PhD

Primary Academic Title

Instructor of Medicine, Division of Oncology, Washington University School of Medicine

Research Interest

Acute myeloid leukemia pathogenesis, syndromes characterized by dysregulated cancer genes

Education

2013: PhD, medical biochemistry, University of Newcastle, Australia

Training

2013 - 2016: Research associate, University of Queensland, Australia
2016 - 2019: Research assocaite, Washington University, St. Louis

Selected Research Publications

Somatic Dnmt3a inactivation leads to slow, canonical DNA methylation loss in murine hematopoietic cells.

Smith AM, Verdoni AM, Abel HJ, [...] Ley TJ
iScience 2022

Functional and epigenetic phenotypes of humans and mice with DNMT3A Overgrowth Syndrome.

Smith AM, LaValle TA, Shinawi M, [...] Ley TJ
Nat Commun 2021

Dnmt3a deficiency in the skin causes focal, canonical DNA hypomethylation and a cellular proliferation phenotype.

Chen DY, Ferguson IM, Braun KA, [...] Smith AM, [...] Ley TJ
Proc Natl Acad Sci USA 2021