John Welch, MD, PhD

John Welch, MD, PhD

Primary Academic Title

Associate Professor of Medicine, Division of Oncology, Section of Stem Cell Biology, Washington University School of Medicine

Research Interest

Understanding pathways of normal myeloid development and leukemic dysregulation of myeloid self-renewal programs. As a model system, I have focused on acute promyelocytic leukemia, which is associated with the t(15;17) translocation and the PML-RARA fusion oncoprotein. Initial exposure of hematopoietic cells to PML-RARA leads to inappropriate self-renewal but not myeloproliferation. We are now focusing on understanding programs that lead to dysregulated self-renewal by PML-RARA, especially retinoid receptor-dependent pathways.


  • 2002: PhD, biomedical sciences, University of California, San Diego
  • 2004: MD, University of California, San Diego


  • 2004 - 2006: Intern and resident, internal medicine, Washington University, St. Louis
  • 2006 - 2010: Fellow, hematology and oncology, Washington University

Journal Articles

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