Familial atypical multiple mole melanoma (FAMMM) syndrome

Definition of familial atypical multiple mole melanoma syndrome

familial atypical multiple mole melanoma syndrome

(fuh-MIH-lee-ul ay-TIH-pih-kul MUL-tih-pul ... MEH-luh-NOH-muh SIN-drome)
An inherited condition marked by the following: (1) one or more first- or second-degree relatives (parent, sibling, child, grandparent, grandchild, aunt, or uncle) with malignant melanoma; (2) many moles, some of which are atypical (asymmetrical, raised, and/or different shades of tan, brown, black, or red) and often of different sizes; and (3) moles that have specific features when examined under a microscope. Familial atypical multiple mole melanoma syndrome increases the risk of melanoma and may increase the risk of pancreatic cancer. Also called FAMMM syndrome.

Source: NCI Dictionary of Cancer Terms