donor lymphocyte infusion

Pronunciation: (DOH-ner LIM-foh-site in-FYOO-zhun)

A type of therapy in which lymphocytes from the blood of a donor are given to a patient who has already received a stem cell transplant from the same donor. The donor lymphocytes may kill remaining cancer cells. Donor lymphocyte infusion is used to treat chronic myelogenous leukemia (CML) that has come back and myeloma. It is being studied in the treatment of other types of cancer.

Source: NCI Dictionary of Cancer Terms

Donor lymphocyte infusion. Lymphocytes (a type of white blood cell) from the blood of a donor are given to a patient. (Panel 1): Blood is taken from a vein in the donor’s arm. The blood flows through an apheresis machine that removes the lymphocytes. The blood is then returned to the donor through a vein in the other arm. (Panel 2): The patient receives the lymphocytes through a catheter in the chest.Infusión de linfocitos de un donante. Se administran a un paciente los linfocitos (un tipo de glóbulo blanco) de la sangre de un donate. (Panel 1): se extrae sangre de una vena del brazo del donante. Se hace pasar la sangre por un aparato de aféresis que extrae los linfocitos. Luego, se devuelve la sangre al donante a través de una vena en el otro brazo. (Panel 2): el paciente recibe los linfocitos a través de un catéter colocado en el pecho.2007-04-13 Date last modified: 2015-10-07