multiple endocrine neoplasia type 2 syndrome
Pronunciation: (MUL-tih-pul EN-doh-krin NEE-oh-PLAY-zhuh ... SIN-drome)
A rare, genetic disorder that affects the endocrine glands and can cause tumors in the thyroid gland, parathyroid glands, and adrenal glands. The affected endocrine glands may make high levels of hormones, which can lead to other medical problems such as high blood pressure and kidney stones. Multiple endocrine neoplasia type 2 syndrome is caused by a mutation (change) in a gene called RET, and is divided into three subtypes (MEN2A, MEN2B, and FMTC). People with all subtypes of multiple endocrine neoplasia type 2 syndrome have an increased risk of medullary thyroid cancer, pheochromocytoma, and parathyroid gland cancer. Also called MEN2, MEN2 syndrome, and multiple endocrine adenomatosis type 2.
Source: NCI Dictionary of Cancer Terms2011-10-20Unusual Cancers of Childhood TreatmentTratamiento de los cánceres poco comunes en la niñez