crizotinib

Definition of crizotinib

crizotinib

(krih-ZOH-tih-nib)
A drug used to treat ALK-positive systemic anaplastic large cell lymphoma in young adults and children aged 1 year and older and ALK-positive or ROS1-positive non-small cell lung cancer. It is used in patients whose cancer has spread to other parts of the body or has come back or not gotten better with other treatment. Crizotinib blocks the proteins made by the ALK and ROS1 genes, which may help keep cancer cells from growing. It is a type of tyrosine kinase inhibitor. Also called Xalkori.

Source: NCI Dictionary of Cancer Terms