allogeneic hematopoietic stem cell transplantation

Definition of allogeneic stem cell transplant

allogeneic stem cell transplant

(A-loh-jeh-NAY-ik stem sel TRANZ-plant)
A procedure in which a patient receives healthy blood-forming cells (stem cells) from a donor to replace their own stem cells that have been destroyed by treatment with radiation or high doses of chemotherapy. In an allogeneic stem cell transplant, the healthy stem cells may come from the blood or bone marrow of a related donor who is not an identical twin of the patient or from an unrelated donor who is genetically similar to the patient. An allogeneic stem cell transplant is most often used to treat blood cancers, such as leukemia and lymphoma, and certain types of blood or immune system disorders.

Source: NCI Dictionary of Cancer Terms