Paget disease

Definition of Paget disease of bone

Paget disease of bone

(PA-jet dih-ZEEZ ...)
A chronic condition in which both the breakdown and regrowth of bone are increased. Paget disease of bone occurs most frequently in the pelvic and leg bones, skull, and lower spine. It is most common in older individuals, and may lead to bone pain, deformities, and fractures. Also called osteitis deformans.

Source: NCI Dictionary of Cancer Terms