Philadelphia chromosome

Definition of Philadelphia chromosome

Philadelphia chromosome

(FIH-luh-DEL-fee-uh KROH-muh-some)
An abnormality of chromosome 22 in which part of chromosome 9 is transferred to it. Bone marrow cells that contain the Philadelphia chromosome are often found in chronic myelogenous leukemia and sometimes found in acute lymphocytic leukemia.

Source: NCI Dictionary of Cancer Terms