Definition of vorinostat


A drug used to treat cutaneous T-cell lymphoma that came back, got worse, or did not get better during or after treatment with two systemic therapies. It is also being studied in the treatment of other types of cancer. Vorinostat blocks certain enzymes needed for cell division and may kill cancer cells. It is a type of histone deacetylase inhibitor. Also called SAHA, suberoylanilide hydroxamic acid, and Zolinza.

Source: NCI Dictionary of Cancer Terms