BRAF inhibitors

Definition of BRAF kinase inhibitor

BRAF kinase inhibitor

(… KY-nays in-HIH-bih-ter)
A substance that blocks a protein called BRAF. BRAF is a kinase enzyme that helps control cell growth and signaling. It may be found in a mutated (changed) form in some types of cancer, including melanoma and colorectal cancer. Blocking mutated BRAF kinase proteins may help keep cancer cells from growing. Some BRAF kinase inhibitors are used to treat cancer.

Source: NCI Dictionary of Cancer Terms