cold-knife conization

Definition of cold knife conization

cold knife conization

(kold nife koh-nih-ZAY-shun)
A procedure in which a cone-shaped piece of abnormal tissue is removed from the cervix using a scalpel or laser knife. Some of the tissue is then checked under a microscope for signs of disease, such as cervical cancer. Cold knife conization may also be used to treat certain cervical conditions. Also called cold knife cone biopsy.

Source: NCI Dictionary of Cancer Terms