dinutuximab

Definition of dinutuximab

dinutuximab (din-yoo-TUK-sih-mab): A drug used with granulocyte-macrophage colony-stimulating factor (GM-CSF), aldesleukin (IL-2), and 13-cis-retinoic acid to treat children with high-risk neuroblastoma. It is used in patients whose disease has gotten better with other anticancer treatment. Dinutuximab binds to a substance called GD2, which is found on some types of cancer cells. Dinutuximab may block GD2 and help the immune system kill cancer cells. It is a type of monoclonal antibody. Also called Ch14.18, MOAB Ch14.18, monoclonal antibody Ch14.18, and Unituxin.

Source: NCI Dictionary of Cancer Terms