T-cell receptor (TCR) gene rearrangement test

Definition of T-cell receptor gene rearrangement test

T-cell receptor gene rearrangement test

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A laboratory test in which cells in a sample of blood or bone marrow are checked to see if there are certain changes in the genes that make receptors on T cells (white blood cells). Testing for these gene changes can tell whether large numbers of T cells with a certain T-cell receptor are being made. This may be a sign of T-cell lymphoma or leukemia.

Source: NCI Dictionary of Cancer Terms