Definition of talazoparib tosylate

talazoparib tosylate

(TA-luh-ZOH-puh-rib TOH-suh-layt)
A drug used to treat adults with HER2-negative breast cancer that is locally advanced or has spread and has certain mutations (changes) in the BRCA1 or BRCA2 gene. It is also being studied in the treatment of other types of cancer. Talazoparib tosylate blocks an enzyme involved in many cell functions, including the repair of DNA damage. Blocking this enzyme may help keep cancer cells from repairing their damaged DNA, causing them to die. Talazoparib tosylate is a type of PARP inhibitor. Also called Talzenna.

Source: NCI Dictionary of Cancer Terms