Polatuzumab vedotin

Definition of polatuzumab vedotin

polatuzumab vedotin

(POH-lah-TOO-zoo-mab veh-DOH-tin)
A drug used with bendamustine hydrochloride and rituximab to treat adults with diffuse large B-cell lymphoma that came back or did not get better after treatment with at least two other anticancer therapies. It is also being studied in the treatment of other types of cancer. Polatuzumab vedotin contains a monoclonal antibody that binds to a protein called CD79B, which is found on B cells (a type of white blood cell) and some lymphoma cells. It also contains an anticancer drug, which may help kill cancer cells. Polatuzumab vedotin is a type of antibody-drug conjugate. Also called Polivy.

Source: NCI Dictionary of Cancer Terms