tucatinib

Definition of tucatinib

tucatinib (too-KA-tih-nib): A drug used with trastuzumab and capecitabine to treat adults with HER2-positive breast cancer that is advanced and cannot be removed by surgery or has spread to other parts of the body, including the brain. It is used in patients whose cancer has already been treated with at least one other anti-HER2 therapy. It is also being studied in the treatment of other types of cancer. Tucatinib blocks a protein called HER2, which may help keep cancer cells from growing and may kill them. It is a type of tyrosine kinase inhibitor. Also called Tukysa.

Source: NCI Dictionary of Cancer Terms