WashU Medicine faculty members affiliated with Siteman Cancer Center will present their research at the 2026 American Society of Clinical Oncology (ASCO) Annual Meeting, May 29-June 2 in Chicago. See the button above for details.
Programming is subject to change. For the most current information, visit the conference program. And be sure to follow Siteman Cancer Center at #ASCO26 on X @SitemanCenter and on Bluesky @sitemancenter.bsky.social.
Siteman News at #ASCO26
WashU Medicine physician-scientists and others affiliated with Siteman Cancer Center will share findings from multi-institutional studies they lead and will present on health equity, mentorship and more.
Bladder Cancer
WashU Medicine medical oncologist Melissa A. Reimers, MD, of Siteman Cancer Center, discussed the high response rates of the phase 2 SAKK 06/19 trial (NCT04630730); highlighted the emerging role of intravesical BCG (Bacillus Calmette-Guérin), a highly effective immunotherapy, in muscle-invasive bladder cancer; questioned perioperative platinum necessity; and stressed defining complete response to evaluate future bladder-sparing, chemoimmunotherapy-based strategies.
- Oncology News Central: Combo Regimen Produces High Response Rates in Phase 2 Bladder Cancer Trial
- Learn more
Breast Cancer
WashU Medicine medical oncologist Emily L. Podany, MD, of Siteman Cancer Center, presented on the impact of food access and poverty on somatic genomic profiles and clinical outcomes in metastatic breast cancer.
- Cure: Food Deserts Link to Aggressive Breast Cancer Biology and Survival Gaps
- Oncology Nursing News: Nursing Strategies to Combat Food Insecurity in Metastatic Breast Cancer
- Learn more
Endometrial Cancer
Model-based predictions from the pivotal phase 3 ENGOT-ENG-NSGO/GOG-3031/RUBY trial (NCT03981796) suggest the potential for cure with dostarlimab-gxly (Jemperli) plus carboplatin and paclitaxel in patients with mismatch repair–deficient (dMMR)/microsatellite instability–high (MSI-H) primary advanced or recurrent endometrial cancer. WashU Medicine gynecologic oncologist Matthew Powell, MD, of Siteman Cancer Center, will present the full data on May 29.
- The ASCO Post: Four-Year RUBY Data Support Curative Intent With Dostarlimab in dMMR/MSI-H Endometrial Cancer
- Cancer Therapy Advisor: Dostarlimab Plus Chemo May Offer Cure to Some Advanced Endometrial Cancer Patients
- Targeted Oncology: Dostarlimab/Chemo Shows Curative Potential in dMMR/MSI-H Advanced Endometrial Cancer
- Cancer Network: Dostarlimab Plus Chemotherapy Yields Curative Potential in dMMR/MSI-H Endometrial Cancer
- Cure: Top Gynecologic Cancer Research to Look Forward to at ASCO 2026
- OncLive:
- Oncology Learning Network: Dostarlimab Plus Chemotherapy Demonstrates Sustained Disease Control in dMMR/MSI-H Advanced Endometrial Cancer
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Hematologic Oncology
WashU Medicine medical oncologist Brad Kahl, MD, of Siteman Cancer Center, shares his thoughts on the science being presented at this year’s conference.
- OncLive:
Lung Cancer
Ramaswamy Govindan, MD, FASCO, the Anheuser Busch Endowed Chair in Medical Oncology and associate chief of oncology at WashU Medicine and Siteman Cancer Center, presented the final overall survival results from the randomized phase III Alliance A081105 trial, which evaluated adjuvant erlotinib versus observation after complete resection of EGFR-mutant non-small cell lung cancer.
- The ASCO Post: Ramaswamy Govindan, MD, FASCO, on EGFR-Mutant NSCLC: Final Overall Survival Results From Alliance A081105
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A new lung cancer screening metric centering on tobacco smoking duration, rather than the current tobacco-pack years measure, decreases potentially missed cancers from 13.3% to 3.9%, while expanding the eligible screening population by 28.8%, according to Brendan Heiden, MD, MS, MBA.
- Medscape: Simpler Screening Criteria Could Catch More Lung Cancers
- ASCO Daily News: New Lung Cancer Screening Criteria Expand Eligibility in Large Veterans Health Administration Study
- The ASCO Post: Brendan Heiden, MD, on Lung Cancer Screening Eligibility: Smoking Duration vs Pack-Years
- OncLive: Zongertinib, Sevabertinib Reshape Treatment Landscape for Patients With HER2-Mutated NSCLC
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Neuroendicrine Tumors
Cabozantinib provided significant improvements in progression-free survival versus placebo in patients with previously treated advanced neuroendocrine tumors regardless of functional status, according to results from a subgroup analysis of the phase 3 CABINET pivotal trial presented by WashU Medicine medical oncologist Nikolaos A. Trikalinos, MD, of Siteman Cancer Center.
- Exelixis Inc.: Exelixis Announces Results from Subgroup Analysis of Phase 3 CABINET Pivotal Trial Evaluating CABOMETYX® (cabozantinib) in Non-Functional and Functional Neuroendocrine Tumors at ASCO 2026
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Building Resilient Multidisciplinary Oncology Teams
WashU Medicine head and neck surgeon John Schneider, MD, MA, FACS, of The Brain Tumor Center at Siteman Cancer Center, and others have debuted a model to help organizations establish and sustain high-functioning multidisciplinary oncology care teams. Schneider will present an education session, “Leadership Rx: Prescriptions for Effective Teams,” at ASCO on May 30.