Li Ding, PhD

Primary Academic Title

Professor of Medicine, Division of Oncology, Section of Stem Cell Biology, Washington University School of Medicine

Research Interest

Identifying and characterizing somatic/germline genetic changes relevant to cancer initiation and progression as well as drug response by integrating various data types, including DNA, RNA and proteomics data. Developing algorithms to facilitate the translation of genomic findings to clinical practice.

Education

1998: PhD, biochemistry, University of Utah, Salt Lake City

Training

1998 - 2999: Postdoctoral fellow, biochemistry, Stanford University, Palo Alto, Calif.

Selected Research Publications

Longitudinal Profiling of Tumor and Immune Compartments Uncovers Patterns of Dysregulation and Associations with Response in Multiple Myeloma.

Ohlstrom DJ, Pilcher WC, Michaud ME, [...] Ding L, [...] Bhasin MK
Blood Cancer Discov 2026

Cellular senescence in human liver under normal aging and cancer.

Karpova A, Li X, Peng CW, [...] Ding L
Cell Genom 2026

Integrative proteogenomic analysis provides molecular insights and clinical significance in gallbladder cancer.

Fu Z, Song Y, Liu F, [...] Ding L, [...] Fan J
Cancer Cell 2026

Biomarkers of response to neoadjuvant palbociclib plus anastrozole in endocrine-resistant estrogen receptor-positive/HER2-negative breast cancer: a phase 2 trial.

Kong T, Mabry A, Highkin M, [...] Ding L, [...] Ma CX
Nat Commun 2026

A single-cell atlas characterizes dysregulation of the bone marrow immune microenvironment associated with outcomes in multiple myeloma.

Pilcher WC, Yao L, Gonzalez-Kozlova E, [...] Ding L, [...] Bhasin M
Nat Cancer 2026

Advancing biological understanding of cellular senescence with computational multiomics.

Li S, Agudelo Garcia PA, Aliferis C, [...] Ding L, [...] Fan R
Nat Genet 2025

Integrative analysis of lung adenocarcinoma across diverse ethnicities and exposures.

Satpathy S, Clark NM, Chen YJ, [...] Ding L, [...] Gillette MA
Cancer Cell 2025

Combined Flt3L and CD40 agonism restores dendritic cell-driven T cell immunity in pancreatic cancer.

Hogg GD, Weinstein AG, Kingston NL, [...] Ding L, [...] DeNardo DG
Sci Immunol 2025

Germline genetic variation impacts clonal hematopoiesis landscape and progression to malignancy.

Liu J, Tran D, Xue L, [...] Ding L, [...] Bolton KL
Nat Genet 2025

Precision proteogenomics reveals pan-cancer impact of germline variants.

Martins Rodrigues F, Terekhanova NV, Imbach KJ, [...] Ding L
Cell 2025

Multi-omic and spatial analysis of mouse kidneys highlights sex-specific differences in gene regulation across the lifespan.

Chen S, Liu R, Mo CK, [...] Ding L, Chen F
Nat Genet 2025

Proteogenomic characterization of non-functional pancreatic neuroendocrine tumors unravels clinically relevant subgroups.

Ji S, Cao L, Gao J, [...] Ding L, [...] Yu X
Cancer Cell 2025

Germline predisposition in multiple myeloma.

Martins Rodrigues F, Jasielec J, Perpich M, [...] Ding L
iScience 2025

RSK1 is an exploitable dependency in myeloproliferative neoplasms and secondary acute myeloid leukemia.

Kong T, Laranjeira ABA, Letson CT, [...] Ding L, [...] Oh ST
Nat Commun 2025

Breaking frontiers with multidisciplinary cancer research.

Caldas C, Chen X, Ding L, Kather JN , Scaltriti M
Nat Cancer 2025

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