South St. Louis County

Siteman Cancer Center’s South St. Louis County facility is located at Interstate 55 and Butler Hill Road and has been in operation since January 2012. We bring world-class cancer care to patients in the greater St. Louis area, southern Mo. and Ill., and beyond. Our 37,000-square-foot complex is a fresh, light-filled space where patients can receive treatment and consult with their physicians. At about 16 acres, the building site incorporates green space for patients and families to enjoy, including land set aside for a future healing garden.

The Washington University medical oncologists, radiation oncologists and surgeons who staff the south county facility also work at Siteman’s main campus in St. Louis and collaborate regularly with other Siteman and Washington University physicians. These doctors practice multidisciplinary care, coordinating schedules with their colleagues so patients can see as many as three physicians in one trip and have their entire treatment plan determined in one visit.

Our south county staff includes registered nurses with specialized training in caring for cancer patients. A research coordinator is also available to talk with patients about possible participation in clinical trials, which provide access to new medications and treatments not available at most cancer centers.

Patients who come to our south county location can also take advantage of a wide range of support services and therapies aimed at helping them feel their best as they undergo treatment for cancer. Some of our programs include Therapeutic Horticulture with the Missouri Botanical Gardens, Pet Therapy with therapy dogs, and virtual programs and services like gentle yoga. We also have trained social workers on staff who can help patients with specific problems at home or at work that might arise during treatment.

PDF of driving directions and a campus map


Video Introduction to South County


Patients and visitors shouldn’t have any difficulty finding a parking space at the south county location. Our building is served by a large lot, and there is no charge to park.  There is also a covered area where drivers can drop patients and guests off at the door.


If you or a loved one requires the use of a wheelchair, they are available to borrow inside the main door.

Treatments and Services

At south county, we offer a wide range of treatments and services, including:

  • Washington University Physician care
  • Chemotherapy and Immunotherapy treatments
  • Blood Transfusions
  • Radiation therapy
  • On-site laboratory services
  • Retail pharmacy services
  • CT and PET scans, MRI and Mammography
  • Access to clinical trials
  • Support programs and materials
  • Scalp cooling
Location Amenities

For the added comfort of our patients and guests, we provide a number of amenities, including:

  • Free Wi-Fi throughout the building
  • An information center for patients and family who wish to research diseases and treatments
  • A lounge where patients who are receiving treatment and their family members can relax, with coffee and vending available
Washington University Cancer Center Pharmacy – South County

Normal business hours:
Monday through Friday 8:00 a.m. to 4:30 p.m.

Pharmacy location:
5225 Midamerica Plaza
St. Louis, MO 63129

Contact information:
Phone:   314-286-1785
Fax:  314-286-1788
Contact:  Tony Druger, Pharm.D.

Support Services

The Siteman Cancer Center offers a variety of support programs for patients and families at all of our locations. These programs range from support groups and exercise programs to educational sessions and pet therapy. Many of our service take place in a virtual format.

The following support programs are offered by Siteman- South County. All programs are held at the cancer center, 5225 Midamerica Plaza St. Louis, MO 63129. For more information, call 314-286-1950.

Therapeutic Horticulture with the Missouri Botanical Gardens

The Therapeutic Horticulture team of the Missouri Botanical Garden brings nature to every Siteman location with activities designed especially for patients who are in infusion units or who have been admitted to an in-patient room. Hands-on activities like arranging flowers and creating herbal tea blends benefit patients’ well-being and encourage their creative expression. These sessions are highly personalized with one-on-one attention from a Therapeutic Horticulture team member and you.

When: Ongoing

Pet Therapy

On a regular basis, pet therapy volunteers take their highly trained and certified dogs to visit patients in both outpatient treatment areas and in-patient units. Interacting with animals have proven physical and mental health benefits for patients and can be a welcome comfort when you are with us. These teams rotate among all of our locations, so their visits times and days vary. You may not see one of our pet therapy teams at every visit. But it gives something to look forward to when they do walk into your room.

When: Ongoing

Nutritional Support

A consultation with a registered dietitian to discuss nutritional needs of patients based on their disease and treatment type.

To learn more, call 314-286-2500.

Social Workers

Social workers are available to help patients and families cope with the challenges and problems caused by cancer. They provide assistance with such issues as lodging and transportation, rehabilitation and hospice care, and advance directives. They also identify community resources related to housing, employment, legal issues and financial concerns. For more information or to reach a social worker at this facility, call 314-286-1106

Siteman Psychology Service

Patients and family members who come to Siteman can make an appointment with a psychologist, free of charge, to discuss the emotional challenges posed by cancer and develop methods for coping.

For more information, visit our Siteman Psychology Service page.

Where can patients see Siteman experts?

In addition to our facility, Siteman is conveniently located in six other locations across the St. Louis metro area. Those locations are: