1418 Cross St., Shiloh, IL 62269

Siteman Cancer Center facility at the Memorial Hospital Shiloh campus in Shiloh, Ill., opened Jan. 13, 2020. The facility marks Siteman’s sixth location overall.

Read more about the opening of this new state-of-the-art facility.

The treatment center offers convenient access to nationally recognized cancer care, including clinical trials, for residents of southern and central Illinois and beyond.

Memorial Hospital Shiloh and Washington University Physicians in Illinois Inc., jointly operate the new Siteman facility.

PDF of driving direction and a campus map


Video Introduction to Memorial Hospital Shiloh




Parking is readily available outside the facility.  You should be able to locate a parking space without much difficulty.


If you or a loved one requires the use of a wheelchair for your visit, please don’t hesitate to borrow one. They may be found just off the main lobby of the facility.

Treatments and Services

New patient questionnaire download (PDF)

Services currently offered at our facility include:

  • Washington University Physician care
  • Chemotherapy treatment
  • Radiation therapy
  • Support programs and resources
  • Scalp cooling

At our Illinois facility, we hope to make your visit more comfortable by offering a number of amenities, including:

  • Free coffee
  • Free WiFi
Support Services

The Siteman Cancer Center offers a variety of support programs for patients and families at all of our locations. These programs range from support groups and exercise programs to educational sessions and pet therapy. Many of our services take place in a virtual format.

The following support programs are offered by Siteman- Illinois. All programs are held at the cancer center, 1418 Cross St., Shiloh, IL 62269. For more information, call (618) 607-1340.

Therapeutic Horticulture with the Missouri Botanical Gardens

The Therapeutic Horticulture team of the Missouri Botanical Garden brings nature to every Siteman location with activities designed especially for patients who are in infusion units or who have been admitted to an in-patient room. Hands-on activities like arranging flowers and creating herbal tea blends benefit patients’ well-being and encourage their creative expression. These sessions are highly personalized with one-on-one attention from a Therapeutic Horticulture team member and you.

When: Ongoing

Pet Therapy

On a regular basis, pet therapy volunteers take their highly trained and certified dogs to visit patients in both outpatient treatment areas and in-patient units. Interacting with animals have proven physical and mental health benefits for patients and can be a welcome comfort when you are with us. These teams rotate among all of our locations, so their visits times and days vary. You may not see one of our pet therapy teams at every visit. But it gives something to look forward to when they do walk into your room.

When: Ongoing

Nutritional Support

A consultation with a registered dietitian to discuss nutritional needs of patients based on their disease and treatment type.

To learn more, call (618) 607-1340, option 2.


Social Workers

Social workers are available to help patients and families cope with the challenges and problems that can arise during cancer treatment. They provide assistance with such issues as lodging and transportation, rehabilitation and hospice care, and advance directives. They can also help patients with problems that are not immediately related to cancer or cancer care, such as housing, employment, legal difficulties, and financial concerns.

To arrange a meeting with a social worker or for more information, call 618-607-1340.

Siteman Psychology Service

Patients and family members who come Siteman can make an appointment with a psychologist, free of charge, to discuss the emotional challenges posed by cancer and develop methods for coping. Offered virtually.

For more information, visit our Siteman Psychology Service page.

What is Siteman Cancer Center? What makes it unique?

Siteman Cancer Center is an international leader in cancer treatment, research, prevention, education and community outreach. With the expertise of more than 450 Washington University research scientists and physicians, Siteman treats 50,000 cancer patients each year. So, tumors often considered rare are frequently treated by Washington University physicians at Siteman.

A full range of advanced diagnostic and treatment services are available at Siteman for patients with all types of cancer. Siteman also offers access to support services and educational resources.

Siteman is one of just 49 National Cancer Institute (NCI)-designated Comprehensive Cancer Centers, which puts Siteman in the top 1 percent of U.S. hospitals in terms of cancer research and care. Siteman is the only such cancer center within 200 miles of St. Clair County, and one of just a few cancer centers nationwide to receive the NCI’s highest rating, “Exceptional,” for its research programs.

As an NCI-designated Comprehensive Cancer Center, Siteman:

  • Provides clinical excellence today.
  • Researches tomorrow’s cures.
  • Pushes scientific findings out into the community, making the research relevant to cancer patients in the very near future.

Siteman also is the region’s only member of the National Comprehensive Cancer Network (NCCN), a nonprofit alliance of the nation’s leading cancer centers dedicated to improving the quality, efficiency and effectiveness of cancer care. As an NCCN member, Siteman plays an integral role in developing resources that present valuable information to cancer patients, health-care providers and other groups by creating guidelines for treatment and clinical practice, distributing clinical trial information and planning educational conferences and literature.

As the region’s only NCI-designated Comprehensive Cancer Center and NCCN member, Siteman also is committed to expanding access to cancer prevention and control strategies, clinical studies and genomic and genetic testing throughout the area, efforts aimed at reducing the burden of cancer on our neighbors and communities.

How does having a Siteman satellite benefit residents of central and southern Illinois?

Having a Siteman Cancer Center satellite in Illinois offers residents more convenient access to specialized care at what is widely recognized as one of the top research-based cancer centers in the nation. Washington University scientists and physicians at Siteman are recipients of $150 million in cancer research grants. The research they conduct, whether in a lab or through clinical trials, can inform the diagnosis and treatment of patients in Illinois, Missouri and beyond. Siteman also conducts more than 400 clinical trials evaluating investigational therapies, including many in collaboration with other leading U.S. cancer centers. Patients at Siteman in Illinois will have access to these trials.

Siteman’s parent institutions, Barnes-Jewish Hospital and Washington University School of Medicine in St. Louis, also are nationally recognized by U.S. News & World Report, which consistently ranks them, and Siteman, among the best institutions of their kind in the nation.

What are clinical trials? Will Siteman Cancer Center offer them in Illinois?

Siteman Cancer Center offers more than 400 therapeutic clinical trials, which are studies designed to evaluate the effectiveness of innovative cancer therapies. By participating in a clinical trial, patients can gain early access to investigational therapies that are not widely available to the public.

What are other benefits of being treated at Siteman Cancer Center?

In addition to having convenient access to highly specialized cancer care, patients in and/or residents of southern and central Illinois benefit from:

  • Streamlined genomic and genetic testing to help identify the cause of a patient’s cancer, and more personalized, targeted treatments based on his or her disease.
  • Continuous improvements to patient care, based on new guidelines for the diagnosis and treatment of cancer, which are updated regularly. Examples include how nurses and radiation therapists are trained to care for oncology patients, and implementing new survivorship and cancer screening recommendations.
  • Implementation of cancer prevention strategies, such as the use of interactive tools, e-books, videos, individual coaching and online cancer risk assessment tools.
Where can patients see Siteman experts?

In addition to our facility, Siteman is conveniently located in six other locations across the St. Louis metro area. Those locations are: