Bhuvic Patel, MD

Bhuvic Patel, MD

Neurosurgeon

Primary Academic Title

Assistant Professor, Department of Neurosurgery, WashU Medicine

Clinical Expertise

Skull base neurosurgery

Research Interest

My laboratory focuses on complex skull base tumors, including pituitary adenomas, meningiomas, and vestibular schwannomas—tumors I frequently encounter in the operating room. We employ advanced molecular techniques like single-cell RNA sequencing, high-resolution spatial transcriptomics, and epigenetic profiling to dissect these tumors at a cellular level. By integrating these data, we aim to unravel the mechanisms driving aggressive tumor behavior and develop novel therapies for tumors resistant to conventional treatments. Our goal is to personalize treatment strategies, improving outcomes for patients with these challenging and often refractory tumors

Education

  • 2011: BS, Brown University
  • 2015: MD, Washington University School of Medicine

Training

  • 2015 - 2022: Neurological Surgery Residency , Washington University School of Medicine, St. Louis, MO
  • 2019 - 2021: Postdoctoral Research Fellowship , Washington University School of Medicine, St. Louis, MO
  • 2022 - 2023: Postdoctoral Research Fellowship , German Cancer Research Center, Heidelberg, Germany
  • 2023 - 2024: Skull Base Neurosurgery Fellowship, University of Pittsburgh Medical Center, Pittsburgh, PA

Selected Research Publications

NF2 loss-of-function and hypoxia drive radiation resistance in grade 2 meningiomas.
  • Patel B, Pugazenthi S, English CW, [...] Kim AH
  • J Natl Cancer Inst 2025
The evolution and application of multi-omic analysis for pituitary neuroendocrine tumors.
  • Pugazenthi S, Pari SS, Zhang Z, [...] Patel B
  • Front Med (Lausanne) 2025

Contact Information

  • Gary C. Werths Building at Siteman Cancer Center

    4500 Forest Park Avenue
    Saint Louis, MO 63108

  • South St. Louis County

    5225 Midamerica Plaza
    St. Louis, MO 63129

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