Daniel Thorek, PhD

Primary Academic Title

Associate Professor of Radiology, Division of Radiological Chemistry and Imaging Laboratory, Washington University School of Medicine

Research Interest

Our laboratory focuses on characterizing disease on a molecular and functional level for the precise application of targeted therapies. Noninvasive imaging and ex vivo profiling provide a basis for the development and monitoring of novel mono- and combination therapy approaches in model systems that recapitulate features of advanced disease.

Education

2009: PhD, bioengineering, University of Pennsylvania, Philadelphia

Selected Research Publications

Quantitative Comparison of SPECT and PET Performance for Clinical Theranostic Applications.

Salerno I, Dunn N, White H, [...] Thorek DLJ
J Nucl Med 2026

Development of a leucine-rich repeat-containing protein 15-targeted radio-immunotheranostic approach to deplete pro-tumorigenic mechanisms and immunotherapy resistance.

Storey CM, Altai M, Lückerath K, [...] Thorek D, Ulmert D
Signal Transduct Target Ther 2025

Optimizing peptide nucleic acid-based pretargeting for enhanced targeted radionuclide therapy.

Altai M, Nagy Á, Granit P, [...] Thorek DLJ, [...] Karlström AE
J Control Release 2025

Impact of biocontainment on small animal PET performance adapted for BSL-2/3 infectious disease imaging research.

Salerno I, Benabdallah N, Fears A, [...] Thorek DLJ
EJNMMI Res 2025

Beyond Average: α-Particle Distribution and Dose Heterogeneity in Bone Metastatic Prostate Cancer.

Benabdallah N, Lu P, Abou DS, [...] Thorek DLJ
J Nucl Med 2024

Molecular Imaging of ACE2 Expression in Infectious Disease and Cancer.

Li Z, Hasson A, Daggumati L, Zhang H, Thorek DLJ
Viruses 2023

Evaluation of Candidate Theranostics for 227Th/89Zr Paired Radioimmunotherapy of Lymphoma.

Abou DS, Longtine M, Fears A, [...] Thorek DLJ
J Nucl Med 2023

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