Fuhai Li, PhD

Primary Academic Title

Associate Professor of Pediatrics, Division of Newborn Medicine, WashU Medicine

Research Interest

Develop computational models for integrative analysis of omics and pharmacogenomics data to predict biomarkers, drugs and drug combinations for cancer treatment

Education

2008: PhD, applied mathematics , Peking University, China

Training

2008 - 2012: Postdoctural, Houston Methodist Hospital Research Institute, Houston

Selected Research Publications

OmniCellTOSG: The First Cell Text-Omic Signaling Graphs Dataset for Graph Language Foundation Modeling.

Zhang H, Xu T, Cao D, [...] Li F
Res Sq 2026

AI for Scientific Discovery in Omics Data-Driven Precision Medicine.

Li F, Zhang H, Huang D, [...] Payne PRO
Mo Med 2026

BioMedGraphica: An All-in-One Platform for Joint Textual Biomedical Prior Knowledge and Numeric Graph Generation.

Zhang H, Liang S, Xu T, [...] Li F
bioRxiv 2025

M3NetFlow: A multi-scale multi-hop graph AI model for integrative multi-omic data analysis.

Zhang H, Goedegebuure SP, Ding L, [...] Li F
iScience 2025

M3NetFlow: A novel multi-scale multi-hop graph AI model for integrative multi-omic data analysis.

Zhang H, Goedegebuure SP, Ding L, [...] Li F
bioRxiv 2024

mosGraphFlow: a novel integrative graph AI model mining disease targets from multi-omic data.

Zhang H, Cao D, Xu T, [...] Li F
bioRxiv 2024

mosGraphGen: a novel tool to generate multi-omics signaling graphs to facilitate integrative and interpretable graph AI model development.

Zhang H, Cao D, Chen Z, [...] Li F
bioRxiv 2024

Using DeepSignalingFlow to mine signaling flows interpreting mechanism of synergy of cocktails.

Zhang H, Chen Y, Payne P, Li F
NPJ Syst Biol Appl 2024

mosGraphGPT: a foundation model for multi-omic signaling graphs using generative AI.

Zhang H, Huang D, Chen E, [...] Li F
bioRxiv 2024

mosGraphGen: a novel tool to generate multi-omics signaling graphs to facilitate integrative and interpretable graph AI model development.

Zhang H, Cao D, Chen Z, [...] Li F
Bioinform Adv 2024

sc2MeNetDrug: A computational tool to uncover inter-cell signaling targets and identify relevant drugs based on single cell RNA-seq data.

Feng J, Goedegebuure SP, Zeng A, [...] Li F
PLoS Comput Biol 2024

Interpreting the Mechanism of Synergism for Drug Combinations Using Attention-Based Hierarchical Graph Pooling.

Dong Z, Zhang H, Chen Y, Payne PRO, Li F
Cancers (Basel) 2023