Kelly Bolton, MD, PhD

Kelly Bolton, MD, PhD

Medical Oncologist

Primary Academic Title

Assistant Professor of Medicine, Division of Oncology Section of Bone Marrow Transplantation & Leukemia, WashU Medicine

Clinical Expertise

Leukemia

Research Interest

The interplay between inherited genetic variation, environmental factors and acquired mutations in shaping earliest carcinogenesis and cancer

Education

  • 2011: PhD, public health and primary care, University of Cambridge, United Kingdom
  • 2013: MD, University of California, Los Angeles

Training

  • 2015 - 2018: Fellow, medical oncology/internal medicine, Memorial Sloan Kettering Cancer Center, New York

Board Certification

  • 2015: American Board of Medicine
  • 2018: American Board of Oncology

Selected Research Publications

Germline alterations in patients with lung cancer.
  • Govindan R, Navo K, Huang M, [...] Bolton K, Cao Y
  • Ann Oncol 2026
Clonal hematopoiesis detection by simultaneous assessment of peripheral blood mononuclear cells, blood plasma, and saliva.
  • Stewart CM, Parpart-Li S, White JR, [...] Bolton KL, [...] Diaz LA
  • J Clin Invest 2025
Integration of Germline and Somatic Variation Improves Chronic Lymphocytic Leukemia Risk Stratification.
  • Hubbard AK, Brown DW, Liu J, [...] Bolton KL, Machiela MJ
  • Cancer Res 2025
Deconvoluting clonal and cellular architecture in IDH-mutant acute myeloid leukemia.
  • Sirenko M, Lee S, Sun Z, [...] Bolton KL, [...] Papaemmanuil E
  • Cell Stem Cell 2025
The Space Omics and Medical Atlas (SOMA) and international astronaut biobank.
  • Overbey EG, Kim J, Tierney BT, [...] Bolton KL, [...] Mason CE
  • Nature 2024
Plasma Proteomic Signature Predicts Myeloid Neoplasm Risk.
  • Tran D, Beeler JS, Liu J, [...] Bolton KL
  • Clin Cancer Res 2024
Clinical and Therapeutic Implications of Clonal Hematopoiesis.
  • Petrone G, Turker I, Natarajan P, Bolton KL
  • Annu Rev Genomics Hum Genet 2024
Germline Predisposition in Hematologic Malignancies: Testing, Management, and Implications.
  • Godley LA, DiNardo CD, Bolton K
  • Am Soc Clin Oncol Educ Book 2024
ArCH: improving the performance of clonal hematopoiesis variant calling and interpretation.
  • Chan ICC, Panchot A, Schmidt E, [...] Bolton KL
  • Bioinformatics 2024

View All Publications

Contact Information

  • Gary C. Werths Building at Siteman Cancer Center

    4500 Forest Park Avenue
    Saint Louis, MO 63108

Phone Numbers

Request an appointment