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A Maintenance Protocol of Sirolimus in Combination With Metronomic Chemotherapy in Children With High-Risk Solid Tumors

  • Protocol Number: 202107132
  • Principal Investigator: Armstrong, Amy
  • Cancer Types: Siteman Kids- Pediatrics

Learn more about this study at: clinicaltrials.gov

For more information on this trial, contact us here:

Phone
800-600-3606
Email
[email protected]

Brief Summary

The primary objective of this study is to improve the 2-year progression-free survival in children with high-risk solid tumors who are administered a maintenance regimen with continuous sirolimus administered on a backbone of metronomic chemotherapy following the completion of standard therapy, as compared to high-risk solid tumor patients treated with observation alone following completion of standard therapy.

Protocol Interventions

Sirolimus, Cyclophosphamide, Etoposide, Celecoxib