Corina Anastasaki, PhD

Primary Academic Title

Assistant Professor of Neurology, Washington University School of Medicine

Research Interest

Cellular and molecular pathogenesis of the Neurofibromatosis type 1 (NF1) cancer predisposition syndrome

Education

2011: PhD, human genetics and molecular biology, Edinburgh University, Scotland, United Kingdom

Training

2015 - 2017: Postdoctoral fellowship, neurology and molecular cell biology, Washington University, St. Louis

Selected Research Publications

NF1 mutation-driven neuronal hyperexcitability sets a threshold for tumorigenesis and therapeutic targeting of murine optic glioma.

Anastasaki C, Chatterjee J, Koleske JP, [...] Gutmann DH
Neuro-oncology 2024

Nf1 mutation disrupts activity-dependent oligodendroglial plasticity and motor learning in mice.

Pan Y, Hysinger JD, Yalçın B, [...] Anastasaki C, [...] Monje M
Nat Neurosci 2024

Next Directions in the Neuroscience of Cancers Arising outside the CNS.

Amit M, Anastasaki C, Dantzer R, [...] Borniger JC
Cancer Discov 2024

A common single nucleotide variant in the cytokine receptor-like factor-3 (CRLF3) gene causes neuronal deficits in human and mouse cells.

Wilson AF, Barakat R, Mu R, [...] Anastasaki C
Hum Mol Genet 2023

Neurons as stromal drivers of nervous system cancer formation and progression.

Anastasaki C, Gao Y, Gutmann DH
Dev Cell 2023

Human induced pluripotent stem cell engineering establishes a humanized mouse platform for pediatric low-grade glioma modeling.

Anastasaki C, Chatterjee J, Cobb O, [...] Gutmann DH
Acta Neuropathol Commun 2022

Neuronal hyperexcitability drives central and peripheral nervous system tumor progression in models of neurofibromatosis-1.

Anastasaki C, Mo J, Chen JK, [...] Gutmann DH
Nat Commun 2022

Generation of human induced pluripotent stem cell-derived cerebral organoids for cellular and molecular characterization.

Anastasaki C, Wilson AF, Chen AS, Wegscheid ML , Gutmann DH
STAR Protoc 2022

RAS and beyond: the many faces of the neurofibromatosis type 1 protein.

Anastasaki C, Orozco P, Gutmann DH
Dis Model Mech 2022