Amanda Cashen, MD

Amanda Cashen, MD

Bone Marrow Transplant Specialist, Medical Oncologist

Primary Academic Title

Professor of Medicine, Division of Oncology, Section of Bone Marrow Transplantation, Associate Chief of Hematologic Malignancies, Washington University School of Medicine

Clinical Expertise

As a member of our leukemia and lymphoma specialist teams, Dr. Cashen cares for patients diagnosed with leukemia and lymphoma through treatment and recovery. Dr. Cashen also has expertise in myelodysplastic syndromes and stem-cell transplantation. Learn more about Dr. Cashen and the Blood and Marrow Transplant Program at Siteman.

Research Interest

I conduct and participate in clinical trials focused on novel therapies for hematologic malignancies.


  • 1999: MD, Washington University, St. Louis


  • 1999 - 2002: Resident, internal medicine, Washington University, St. Louis
  • 2003 - 2006: Fellow, hematology-oncology, Washington University

Board Certification

  • 2002: American Board of Internal Medicine, Internal Medicine
  • 2006: American Board of Internal Medicine, Medical Oncology

Selected Research Publications

A phase II study of interrupted and continuous dose lenalidomide in relapsed/refractory Hodgkin lymphoma.
  • Fehniger TA, Watkins MP, Ezenwajiaku N, [...] Cashen AF, [...] Bartlett NL
  • Haematologica 2024
KDM6B protects T-ALL cells from NOTCH1-induced oncogenic stress.
  • Issa N, Bjeije H, Wilson ER, [...] Cashen A, [...] Challen GA
  • Leukemia 2023
Autologous T cell therapy for MAGE-A4+ solid cancers in HLA-A*02+ patients: a phase 1 trial.
  • Hong DS, Van Tine BA, Biswas S, [...] Cashen A, [...] Butler MO
  • Nat Med 2023
Long-term outcomes for ibrutinib-rituximab and chemoimmunotherapy in CLL: updated results of the E1912 trial.
  • Shanafelt TD, Wang XV, Hanson CA, [...] Cashen AF, [...] Kay NE
  • Blood 2022
Decitabine salvage for TP53-mutated, relapsed/refractory acute myeloid leukemia after cytotoxic induction therapy.
  • Ferraro F, Gruszczynska A, Ruzinova MB, [...] Cashen AF, [...] Welch JS
  • Haematologica 2022
Stem cell transplant for lymphoma - never too late?
  • Cashen AF, Bartlett NL
  • Haematologica 2022
Donor memory-like NK cells persist and induce remissions in pediatric patients with relapsed AML after transplant.
  • Bednarski JJ, Zimmerman C, Berrien-Elliott MM, [...] Cashen AF, Fehniger TA
  • Blood 2022
Systemic IL-15 promotes allogeneic cell rejection in patients treated with natural killer cell adoptive therapy.
  • Berrien-Elliott MM, Becker-Hapak M, Cashen AF, [...] Fehniger TA
  • Blood 2022
Hematopoietic cell transplantation donor-derived memory-like NK cells functionally persist after transfer into patients with leukemia.
  • Berrien-Elliott MM, Foltz JA, Russler-Germain DA, [...] Cashen AF, Fehniger TA
  • Sci Transl Med 2022
Determining subpopulation methylation profiles from bisulfite sequencing data of heterogeneous samples using DXM.
  • Fong J, Gardner JR, Andrews JM, Cashen AF, [...] Edwards JR
  • Nucleic Acids Res 2021
Loss of synergistic transcriptional feedback loops drives diverse B-cell cancers.
  • Andrews JM, Pyfrom SC, Schmidt JA, [...] Cashen AF, [...] Payton JE
  • EBioMedicine 2021
Phase I Trial of N-803, an IL15 Receptor Agonist, with Rituximab in Patients with Indolent Non-Hodgkin Lymphoma.
  • Foltz JA, Hess BT, Bachanova V, [...] Cashen AF, [...] Fehniger TA
  • Clin Cancer Res 2021

Contact Information

  • Washington University Medical Campus

    4921 Parkview Place
    Saint Louis, MO 63110

Phone Numbers

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