Feng Chen, PhD

Feng Chen, PhD

Primary Academic Title

Associate Professor of Medicine, Washington University School of Medicine

Research Interest

The genetic determinants and pathogenic mechanisms of benign and malignant urogenital diseases with the goal of improving diagnostic and therapeutic strategies targeting these diseases. Creating and utilizing an array of experimental and disease models in mice to study the involvement of calcineurin-NFAT and other pathways in CAKUT (Congenital Anomalies of the Kidney and the Urinary tract), glomerular diseases, and urogenital cancers.

Education

  • 1998: PhD, human genetics, University of Utah School of Medicine, Salt Lake City

Training

  • 1998 - 2002: Fellow, molecular genetics, Stanford University, Palo Alto, Calif.

Selected Research Publications

DeST-OT: Alignment of spatiotemporal transcriptomics data.
  • Halmos P, Liu X, Gold J, Chen F, [...] Raphael BJ
  • Cell Syst 2025
SenNet recommendations for detecting senescent cells in different tissues.
  • Suryadevara V, Hudgins AD, Rajesh A, [...] Chen F, [...] Neretti N
  • Nat Rev Mol Cell Biol 2024
Differential chromatin accessibility and transcriptional dynamics define breast cancer subtypes and their lineages.
  • Iglesia MD, Jayasinghe RG, Chen S, [...] Chen F, [...] Ding L
  • Nat Cancer 2024
Tumour evolution and microenvironment interactions in 2D and 3D space.
  • Mo CK, Liu J, Chen S, [...] Chen F, Ding L
  • Nature 2024
Multi-scale signaling and tumor evolution in high-grade gliomas.
  • Liu J, Cao S, Imbach KJ, [...] Chen F, [...] Ding L
  • Cancer Cell 2024
Comprehensive proteogenomic characterization of rare kidney tumors.
  • Li GX, Chen L, Hsiao Y, [...] Chen F, [...] Nesvizhskii AI
  • Cell Rep Med 2024
Epigenetic regulation during cancer transitions across 11 tumour types.
  • Terekhanova NV, Karpova A, Liang WW, [...] Chen F, [...] Ding L
  • Nature 2023
Single-Cell Discovery and Multiomic Characterization of Therapeutic Targets in Multiple Myeloma.
  • Yao L, Wang JT, Jayasinghe RG, [...] Chen F, [...] DiPersio JF
  • Cancer Res 2023

View All Publications