Matthew Cooper, PhD

Primary Academic Title

Assistant Professor of Medicine, Division of Bone Marrow Transplant, Washington University School of Medicine

Research Interest

Immunology, bone marrow transplantation, hematological malignancies and target therapies for the treatment of hematologic cancers; CRISPR/Cas9 gene editing techniques to enhance CAR-T therapy for treatment of T cell hematological malignancies

Education

2008: PhD, cancer genetics, University of Surrey, United Kingdom

Training

2011 - 2014: Postdoctoral research associate, Washington University, St. Louis

Selected Research Publications

An "off-the-shelf" CD2 universal CAR-T therapy for T-cell malignancies.

Xiang J, Devenport JM, Carter AJ, [...] Cooper ML, DiPersio JF
Leukemia 2023

CS1 CAR-T targeting the distal domain of CS1 (SLAMF7) shows efficacy in high tumor burden myeloma model despite fratricide of CD8+CS1 expressing CAR-T cells.

O'Neal J, Ritchey JK, Cooper ML, [...] DiPersio JF
Leukemia 2022

Baricitinib prevents GvHD by increasing Tregs via JAK3 and treats established GvHD by promoting intestinal tissue repair via EGFR.

Kim S, Ashami K, Lim S, [...] Cooper ML, [...] Choi J
Leukemia 2022

Antibody-drug conjugates plus Janus kinase inhibitors enable MHC-mismatched allogeneic hematopoietic stem cell transplantation.

Persaud SP, Ritchey JK, Kim S, [...] Cooper ML, [...] DiPersio JF
J Clin Invest 2021

Siteman Cancer Center ranked No. 10 among U.S. cancer centers

Diversity, Equity & Inclusion at Siteman

How Siteman is leading the way in personalized brain tumor treatment

Siteman Cancer Center expands proton therapy treatment

Siteman explains what every woman should know about endometrial cancer risk, symptoms and screening

Immunity boosting treatment enhances CAR-T cell therapy for blood cancers

$5.3 million grant supports research into lung cancer recurrence

Couple honors physician with gift for distinguished professorship

Siteman Cancer Center ranked No. 10 among U.S. cancer centers

Siteman Cancer Center ranked No. 10 among U.S. cancer centers

Diversity, Equity & Inclusion at Siteman

How Siteman is leading the way in personalized brain tumor treatment

Treatment
Clinical
How Siteman is leading the way in personalized brain tumor treatment
If you or a loved one have recently been diagnosed with a brain tumor, you likely feel a great deal of fear and have many questions. The brain is the epicenter of who we are,...
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How Siteman is leading the way in personalized brain tumor treatment

Cancer Types

The Siteman Approach

Specialized Programs

Siteman Cancer Center expands proton therapy treatment

Siteman Cancer Center expands proton therapy treatment

Siteman explains what every woman should know about endometrial cancer risk, symptoms and screening

Siteman explains what every woman should know about endometrial cancer risk, symptoms and screening

Immunity boosting treatment enhances CAR-T cell therapy for blood cancers

Immunity boosting treatment enhances CAR-T cell therapy for blood cancers

$5.3 million grant supports research into lung cancer recurrence

$5.3 million grant supports research into lung cancer recurrence

Couple honors physician with gift for distinguished professorship

Couple honors physician with gift for distinguished professorship

Matthew Cooper, PhD

Primary Academic Title

Research Interest

Education

Training

Selected Research Publications