David  Curiel, MD, PhD

David Curiel, MD, PhD

Primary Academic Title

Professor of Radiation Oncology, Division of Cancer Biology, Washington University School of Medicine

Research Interest

Gene therapy, virotherapy and vaccinology.


  • 1982: MD, Emory University, Atlanta
  • 2002: PhD, virology, University of Groningen, Groningen, Netherlands


  • 1982 - 1985: Intern and resident, internal medicine, Emory University, Atlanta
  • 1985 - 1989: Fellow, pulmonary medicine, National Heart, Lung and Blood Institute, Bethesda, Md.
  • 1989 - 1990: Fellow, biotechnology, Navy Medical Oncology Branch, National Cancer Institute, Bethesda

Selected Research Publications

Engineering a Novel Modular Adenoviral mRNA Delivery Platform Based on Tag/Catcher Bioconjugation.
  • Geng K, Rice-Boucher PJ, Kashentseva EA, [...] Curiel DT
  • Viruses 2023
Adenoviral vectors infect B lymphocytes in vivo.
  • Rice-Boucher PJ, Mendonça SA, Alvarez AB, [...] Curiel DT
  • Mol Ther 2023
In vivo editing of the pan-endothelium by immunity evading simian adenoviral vector.
  • Lorincz R, Alvarez AB, Walkey CJ, [...] Curiel DT
  • Biomed Pharmacother 2023
A Novel Piggyback Strategy for mRNA Delivery Exploiting Adenovirus Entry Biology.
  • Lee M, Rice-Boucher PJ, Collins LT, [...] Curiel DT
  • Viruses 2022
Mucopolysaccharidoses type I gene therapy.
  • Hurt SC, Dickson PI, Curiel DT
  • J Inherit Metab Dis 2021
Understanding and addressing barriers to successful adenovirus-based virotherapy for ovarian cancer.
  • Gonzalez-Pastor R, Goedegebuure PS, Curiel DT
  • Cancer Gene Ther 2021
The NIH Somatic Cell Genome Editing program.
  • Saha K, Sontheimer EJ, Brooks PJ, [...] Curiel DT, [...] Zhou J
  • Nature 2021
Mesenchymal Stem Cells Successfully Deliver Oncolytic Virotherapy to Diffuse Intrinsic Pontine Glioma.
  • Chastkofsky MI, Pituch KC, Katagi H, [...] Curiel DT, [...] Balyasnikova IV
  • Clin Cancer Res 2021

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