Dennis Goldfarb, PhD

Dennis Goldfarb, PhD

Primary Academic Title

Assistant Professor, Department of Cell Biology and Physiology, Washington University School of Medicine

Research Interest

Understanding mechanisms in cellular biology and disease; using machine learning, statistical modeling and computer science to improve protein identification/quantification and to create novel analytical capabilities.

Education

  • 2018: PhD, computer science, University of North Carolina, Chapel Hill

Training

  • 2018 - 2019: Postdoctoral research associate, mass spectrometry and proteomics, University of North Carolina

Selected Research Publications

APC/C-mediated ubiquitylation of extranucleosomal histone complexes lacking canonical degrons.
  • Skrajna A, Bodrug T, Martinez-Chacin RC, [...] Goldfarb D, [...] McGinty RK
  • Nat Commun 2025
Engineered Cas9 variants bypass Keap1-mediated degradation in human cells and enhance epigenome editing efficiency.
  • Chen J, Su S, Pickar-Oliver A, [...] Goldfarb D, [...] Liu P
  • Nucleic Acids Res 2024
Structural basis of paralog-specific KDM2A/B nucleosome recognition.
  • Spangler CJ, Skrajna A, Foley CA, [...] Goldfarb D, McGinty RK
  • Nat Chem Biol 2023

View All Publications