David Gutmann, MD, PhD

David Gutmann, MD, PhD

Neurologist

Primary Academic Title

Director, Neurofibromatosis Center; Donald O. Schnuck Family Chair and Professor of Neurology, Washington University School of Medicine

Clinical Expertise

Inherited cancer syndromes

Research Interest

The molecular biology of nervous system tumors, including neurofibromatosis 1, neurofibromatosis 2 and tuberous sclerosis 2 tumor suppressor gene products.

Education

  • 1980: MS, human genetics, University of Michigan, Ann Arbor
  • 1984: PhD, microbiology and immunology, University of Michigan, Ann Arbor
  • 1986: MD, University of Michigan

Training

  • 1986 - 1990: Resident, neurology, University of Pennsylvania, Philadelphia
  • 1990 - 1993: Postdoctoral fellow, human molecular genetics, Howard Hughes Medical Institute and University of Michigan, Ann Arbor

Board Certification

  • 1992: American Board of Psychiatry and Neurology, Neurology

Selected Research Publications

Precision preclinical modeling to advance cancer treatment.
  • Gutmann DH, Boehm JS, Karlsson EK, [...] Snyder JC
  • J Natl Cancer Inst 2025
Precocious Puberty in Children with Neurofibromatosis Type 1.
  • Katz J, Ratnam S, Listernick RH, Habiby RL, Gutmann DH
  • J Pediatr 2025
Integrating priorities at the intersection of cancer and neuroscience.
  • Hwang WL, Perrault EN, Birbrair A, [...] Gutmann DH, [...] Amit M
  • Cancer Cell 2025
Nf1 mutation disrupts activity-dependent oligodendroglial plasticity and motor learning in mice.
  • Pan Y, Hysinger JD, Yalçın B, [...] Gutmann DH, Monje M
  • Nat Neurosci 2024
Next Directions in the Neuroscience of Cancers Arising outside the CNS.
  • Amit M, Anastasaki C, Dantzer R, [...] Gutmann DH, Borniger JC
  • Cancer Discov 2024
Estrogen-induced glial IL-1β mediates extrinsic retinal ganglion cell vulnerability in murine Nf1 optic glioma.
  • Tang Y, Chatterjee J, Wagoner N, Bozeman S, Gutmann DH
  • Ann Clin Transl Neurol 2024

View All Publications

Contact Information

  • Washington University Medical Campus

    Gary C. Werths Building at Siteman Cancer Center
    4500 Forest Park Avenue
    Saint Louis, MO 63108

    Center for Advanced Medicine at Siteman Cancer Center
    4921 Parkview Place
    Saint Louis, MO 63110

    Parkview Tower
    1 Parkview Place
    Saint Louis, MO 63110

    S. Lee Kling Proton Therapy Center
    224 Euclid Ave.
    Saint Louis, MO 63110

    Siteman Kids at St. Louis Children’s Hospital
    1 Children's Place
    St. Louis, MO 63110

Phone Numbers

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