Richard Harbison, MD, MS

Richard Harbison, MD, MS

Head and Neck

Primary Academic Title

Assistant Professor of Otolaryngology, WashU Medicine

Clinical Expertise

Otolaryngology – Head and Neck Cancer

Research Interest

My research is centered on understanding the complex interactions between cancer and the immune system, with a particular focus on how metabolism influences these interactions. A key aspect of my research involves investigating how diet-induced metabolic alterations affect the tumor microenvironment and subsequently modulate anti-tumor immune cell function. In parallel, we are working to identify how malignant cells manipulate the local metabolic milieu to evade the anti-tumor immune response. Our goal is to identify metabolic vulnerabilities within the tumor microenvironment that can be targeted to enhance anti-tumor immunity paving the way for innovative treatments that harness the full potential of the immune system to combat cancer.

Education

  • 2009: BS, University of Denver, Denver CO
  • 2013: MD, University of Colorado - Anschutz Medical Campus, Aurora, CO
  • 2017: MS, University of Washington Seattle, WA

Training

  • 2013 - 2014: Intern, General Surgery , University of Washington, Seattle, WA
  • 2015 - 2017: T32 Postdoctoral Research Fellowship, University of Washington , Seattle, WA
  • 2014 - 2020: Resident, Otolaryngology - Head & Neck Surgery , University of Washington, Seattle, WA
  • 2020 - 2021: Postdoctoral Research Fellowship, Immunometabolism, Johns Hopkins University School of Medicine, Baltimore, MD
  • 2021 - 2022: Fellowship, Head and Neck Surgical Oncology , Johns Hopkins University School of Medicine, Baltimore, MD

Board Certification

  • 2022: American Board of Otolaryngology - Head and Neck Surgery

Selected Research Publications

Immunotherapeutic strategies in head and neck cancer: challenges and opportunities.
  • Liu X, Harbison RA, Varvares MA, Puram SV , Peng G
  • J Clin Invest 2025
Tumor extracellular vesicle-derived PD-L1 promotes T cell senescence through lipid metabolism reprogramming.
  • Ma F, Liu X, Zhang Y, [...] Harbison RA, [...] Peng G
  • Sci Transl Med 2025

View All Publications

Contact Information

  • Gary C. Werths Building at Siteman Cancer Center

    4500 Forest Park Avenue
    Saint Louis, MO 63108

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