Joseph Ippolito, MD, PhD

Joseph Ippolito, MD, PhD

Radiologist

Primary Academic Title

Associate Professor of Radiology, Mallinckrodt Institute of Radiology, Associate Professor of Biochemistry and Molecular Biophysics, Director, Center for Clinical Imaging Research (CCIR), WashU Medicine

Clinical Expertise

Radiology, abdominal imaging, magnetic resonance imaging

Research Interest

Precision medicine through metabolism-based imaging and therapy: from laboratory to clinical translation. My major research focus is two-part. First, we are developing new clinical molecular imaging research technologies with MRI and mass spectrometry to predict poor outcomes in patients with prostate cancer at the time of diagnosis. Second, we are discovering the molecular basis for the effects of biological sex on cancer metabolism, identifying new methods on how imaging and therapy can be applied differently to males and females with cancer to improve outcomes for all.

Education

  • 2007: PhD, molecular biophysics, Washington University, St. Louis
  • 2007: MD, Washington University

Training

  • 2008 - 2012: Resident, diagnostic radiology, Mallinckrodt Institute of Radiology, St. Louis
  • 2012 - 2013: Fellow, body magnetic resonance imaging, Mallinckrodt Institute of Radiology

Board Certification

  • 2012: American Board of Radiology, diagnostic radiology

Selected Research Publications

NCCN Guidelines® Insights: Prostate Cancer, Version 5.2026.
  • Spratt DE, Srinivas S, Adra N, [...] Ippolito JE, [...] Freedman-Cass D
  • J Natl Compr Canc Netw 2026
Prostate Cancer, Version 3.2026, NCCN Clinical Practice Guidelines In Oncology.
  • Spratt DE, Srinivas S, Adra N, [...] Ippolito JE, [...] Freedman-Cass D
  • J Natl Compr Canc Netw 2025
Tumour evolution and microenvironment interactions in 2D and 3D space.
  • Mo CK, Liu J, Chen S, [...] Ippolito JE, [...] Ding L
  • Nature 2024
Epigenetic developmental mechanisms underlying sex differences in cancer.
  • Rubin JB, Abou-Antoun T, Ippolito JE, [...] Yang L
  • J Clin Invest 2024
NCCN Guidelines® Insights: Prostate Cancer, Version 3.2024.
  • Schaeffer EM, Srinivas S, Adra N, [...] Ippolito JE, [...] Freedman-Cass DA
  • J Natl Compr Canc Netw 2024
Prostate Cancer, Version 4.2023, NCCN Clinical Practice Guidelines in Oncology.
  • Schaeffer EM, Srinivas S, Adra N, [...] Ippolito JE, [...] Freedman-Cass DA
  • J Natl Compr Canc Netw 2023

View All Publications

Contact Information

  • Center for Advanced Medicine at Siteman Cancer Center

    4921 Parkview Place
    Saint Louis, MO 63110

Phone Numbers

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