Charles Kaufman, MD, PhD

Charles Kaufman, MD, PhD

Medical Oncologist

Primary Academic Title

Associate Professor of Medicine, Division of Medical Oncology, Washington University School of Medicine

Clinical Expertise

Melanoma, skin cancers

Research Interest

My goal as a physician-scientist is to interface between medicine and basic science to confront challenging fundamental questions in cancer biology. In particular, I study the molecular regulation of cancer initiation - the events that occur at the very start of tumor formation - during which cells readopt stem cell-like characteristics.


  • 2005: MD, University of Chicago
  • 2003: PhD, molecular genetics and cell biology, University of Chicago


  • 2005 - 2007: Resident, internal medicine, Brigham and Women's Hospital, Boston
  • 2007 - 2011: Fellow, hematology/oncology, Massachusetts General Hospital, Boston
  • 2008 - 2016: Postdoctoral research fellow, Boston Children's Hospital

Board Certification

  • 2008: American Board of Internal Medicine
  • 2010: American Board of Internal Medicine - Medical Oncology

Selected Research Publications

Functional analysis of recurrent CDC20 promoter variants in human melanoma.
  • Godoy PM, Oyedeji A, Mudd JL, [...] Kaufman CK
  • Commun Biol 2023
Epigenetic dynamics shaping melanophore and iridophore cell fate in zebrafish.
  • Jang HS, Chen Y, Ge J, [...] Kaufman CK, [...] Wang T
  • Genome Biol 2021
Isotope tracing in adult zebrafish reveals alanine cycling between melanoma and liver.
  • Naser FJ, Jackstadt MM, Fowle-Grider R, [...] Kaufman CK, [...] Patti GJ
  • Cell Metab 2021
Functional in vivo characterization of sox10 enhancers in neural crest and melanoma development.
  • Cunningham RL, Kramer ET, DeGeorgia SK, [...] Kaufman CK
  • Commun Biol 2021
Melanoma models for the next generation of therapies.
  • Patton EE, Mueller KL, Adams DJ, [...] Kaufman CK, [...] Merlino G
  • Cancer Cell 2021

View All Publications

Contact Information

  • South St. Louis County

    5225 Midamerica Plaza
    St. Louis, MO 63129

Phone Numbers

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