Eynav Klechevsky, PhD

Eynav Klechevsky, PhD

Primary Academic Title

Assistant Professor of Pathology and Immunology, Division of Immunobiology, Washington University School of Medicine

Research Interest

Human dendritic cells (DC), a specialized family of antigen presenting cells that elicit immunity to infections and tolerance to self. DCs are composed of subsets endowed with unique functional properties. We study the mechanisms by which distinct human DC subsets control immunity and tolerance and use this information to devise immune strategies for therapeutic intervention in chronic conditions such as cancer.

Education

  • 2007: PhD, immunology, Baylor Institute of Immunology Research, Dallas

Selected Research Publications

A human STAT3 gain-of-function variant drives local Th17 dysregulation and skin inflammation in mice.
  • Toth KA, Schmitt EG, Kolicheski A, [...] Klechevsky E, [...] Cooper MA
  • J Exp Med 2024

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