Eric C. Leuthardt, MD

Eric C. Leuthardt, MD

Neurosurgeon, Surgeon

Primary Academic Title

Shi H. Huang Professor of Neurological Surgery and Neuroscience, Washington University School of Medicine

Clinical Expertise

As director of the Brain Laser Center and a member of our brain tumor specialist team, Dr. Leuthardt cares for patients diagnosed with brain tumors through treatment and recovery. Dr. Leuthardt also has expertise in spine surgery and the surgical treatment of epilepsy. Learn more about Dr. Leuthardt and the Brain Tumor Center at Siteman.

Research Interest

Neuroprosthetics – devices linked to the brain that may lead to cures for paralysis, allow patients to move artificial limbs or restore other neurological functions.

Brain Mapping – developing advanced techniques to locate and preserve critical areas of brain function.


  • 1999: MD, University of Pennsylvania, Philadelphia


  • 1999 - 2001: Intern, general surgery, Washington University, St. Louis
  • 2001 - 2005: Resident and chief resident, neurosurgery, Washington University
  • 2005 - 2006: Fellow, epilepsy and spine surgery, University of Washington, Seattle

Board Certification

  • 2010: American Board of Neurological Surgery

Selected Research Publications

Glioblastoma-infiltrating CD8+ T cells are predominantly a clonally expanded GZMK+ effector population.
  • Wang AZ, Mashimo BL, Schaettler MO, [...] Leuthardt EC, [...] Dunn GP
  • Cancer Discov 2024
Predicting survival in glioblastoma with multimodal neuroimaging and machine learning.
  • Luckett PH, Olufawo M, Lamichhane B, [...] Leuthardt EC
  • J Neurooncol 2023
The Conventional Dendritic Cell 1 Subset Primes CD8+ T Cells and Traffics Tumor Antigen to Drive Antitumor Immunity in the Brain.
  • Bowman-Kirigin JA, Desai R, Saunders BT, [...] Leuthardt EC, [...] Dunn GP
  • Cancer Immunol Res 2023
Structural gray matter alterations in glioblastoma and high-grade glioma-A potential biomarker of survival.
  • Lamichhane B, Luckett PH, Dierker D, [...] Leuthardt EC
  • Neurooncol Adv 2023
Characterization of the Genomic and Immunologic Diversity of Malignant Brain Tumors through Multisector Analysis.
  • Schaettler MO, Richters MM, Wang AZ, [...] Leuthardt EC, [...] Dunn GP
  • Cancer Discov 2022

View All Publications

Contact Information

  • Washington University Medical Campus

    4921 Parkview Place
    Saint Louis, MO 63110

Phone Numbers

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