Kian-Huat Lim, MD, PhD

Kian-Huat Lim, MD, PhD

Medical Oncologist

Primary Academic Title

Associate Professor of Medicine, Division of Oncology, Section of Medical Oncology, Washington University School of Medicine

Clinical Expertise

Gastrointestinal oncology, colorectal cancer, pancreatic cancer, hepatobiliary cancer, novel therapeutics, clinical trial.

Research Interest

Understanding the signaling interplay between the inflammatory and oncogenic pathways, how they affect tumor initiation, progression and response to treatments, and translating these findings into novel treatments for patients. Clinical interest in gastrointestinal such as colorectal, pancreatic and hepatobiliary cancers.


  • 1999: MD, National Taiwan University College of Medicine, Taipei, Taiwan
  • 2006: PhD, molecular cancer biology program, Duke University, Durham, N.C.


  • 1998 - 1999: Intern, National Taiwan University Hospital, Taipei, Taiwan
  • 1999 - 2002: Resident, internal medicine, National Taiwan University Hospital, Taipei, Taiwan
  • 2007 - 2009: Resident, internal medicine, Washington University, St. Louis
  • 2009 - 2010: Fellow, hematology and oncology, Washington University, St. Louis
  • 2010 - 2013: Fellow, medical oncology, National Cancer Institute, National Institutes of Health, Bethesda, Md.

Board Certification

  • 2011: American Board of Internal Medicine

Selected Research Publications

Defining the KRAS- and ERK-dependent transcriptome in KRAS-mutant cancers.
  • Klomp JA, Klomp JE, Stalnecker CA, [...] Lim KH, [...] Der CJ
  • Science 2024
IRAK4 Signaling Drives Resistance to Checkpoint Immunotherapy in Pancreatic Ductal Adenocarcinoma.
  • Somani VK, Zhang D, Dodhiawala PB, [...] Lim KH
  • Gastroenterology 2022
Phase 1 study combining alisertib with nab-paclitaxel in patients with advanced solid malignancies.
  • Lim KH, Opyrchal M, Acharya A, [...] Wang-Gillam A
  • Eur J Cancer 2021

View All Publications

Contact Information

  • West St. Louis County

    Medical Office Building 2, 10 Barnes West Drive
    Creve Coeur, MO 63141

  • Washington University Medical Campus

    4921 Parkview Place
    Saint Louis, MO 63110

Phone Numbers

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