Kiran Mahajan, PhD

Kiran Mahajan, PhD

Primary Academic Title

Assistant Professor of Surgery, Division of Urologic Surgery, Washington University School of Medicine

Research Interest

Employing human prostate organoid model systems and immunocompetent Genetically Engineered Mouse models (GEM) models of prostate cancer to develop and characterize novel small molecule inhibitors to uncover their therapeutic potential and mechanism of action for targeting clinically significant prostate cancers. A second major interest of the lab, is the epigenetic regulation of DNA damage signaling pathways in prostate and breast cancers.

Education

  • 1998: PhD, Indian Institute of Science, Bangalore, India

Training

  • 1998 - 2004: Postgraduate training, Lineberger Comprehensive Cancer Center, Chapel Hill, NC

Selected Research Publications

Prostate cancer immunotherapy: Improving clinical outcomes with a multi-pronged approach.
  • Sridaran D, Bradshaw E, DeSelm C, [...] Mahajan K, Mahajan NP
  • Cell Rep Med 2023
Histone H2A Lys130 acetylation epigenetically regulates androgen production in prostate cancer.
  • Nguyen T, Sridaran D, Chouhan S, [...] Mahajan K, Mahajan NP
  • Nat Commun 2023
Loss of Long Noncoding RNA NXTAR in Prostate Cancer Augments Androgen Receptor Expression and Enzalutamide Resistance.
  • Ghildiyal R, Sawant M, Renganathan A, Mahajan K, [...] Mahajan NP
  • Cancer Res 2022

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