Nupam Mahajan, PhD

Primary Academic Title

Professor of Surgery, Endowed Professor of Urological Research, Division of Surgery, WashU Medicine

Research Interest

Obtaining a fundamental understanding of various epigenetic events that a play crucial role in initiation and progression of prostate and beast cancer

Education

1997: PhD, Indian Institute of Science, Bangalore, India

Selected Research Publications

ACK1/TNK2 kinase: molecular mechanisms and emerging cancer therapeutics.

Sridaran D, Mahajan NP
Trends Pharmacol Sci 2025

SHP2 as a primordial epigenetic enzyme expunges histone H3 pTyr-54 to amend androgen receptor homeostasis.

Chouhan S, Sridaran D, Weimholt C, [...] Mahajan NP
Nat Commun 2024

Epigenetic underpinnings of tumor-immune dynamics in prostate cancer immune suppression.

Angappulige DH, Mahajan NP, Mahajan K
Trends Cancer 2024

Prostate cancer immunotherapy: Improving clinical outcomes with a multi-pronged approach.

Sridaran D, Bradshaw E, DeSelm C, [...] Mahajan NP
Cell Rep Med 2023

Epigenetic reprogramming of cell cycle genes by ACK1 promotes breast cancer resistance to CDK4/6 inhibitor.

Sawant M, Wilson A, Sridaran D, [...] Mahajan NP
Oncogene 2023

Histone H2A Lys130 acetylation epigenetically regulates androgen production in prostate cancer.

Nguyen T, Sridaran D, Chouhan S, [...] Mahajan NP
Nat Commun 2023

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